Orthogon Therapeutics完成超額認購520萬美元的融資,用以研發第一款BK多瘤病毒口服療法

[#item_full_content]麻薩諸塞州,坎頓–(BUSINESS WIRE)–(美國商業資訊)– 專事開發新款抗病毒藥物的Orthogon Therapeutics今天宣布完成一輪超額認購520萬美元的融資,融資數額超過原先設定的500萬美元目標,並讓該公司的融資總額突破2500萬美元。該公司將用這筆融資來加速開發控制接受移植手術患者體內BK病毒再活化的一流療法。 該公司已成功研發數種小分子藥物,可直接靶向多瘤病毒生命週期所必需的病毒蛋白。多瘤病毒沒有常見的抗病毒蛋白質標靶,因此幾十年來一直未能開發出相關藥物。在多元投資者群體和具有獨特作用機制的一系列藥物支持下,Orthogon正在迎戰這個有迫切需要卻尚未得到滿足的醫療需求。 「我們的高親和性小分子抗病毒藥物可媲美生物製劑,但沒有它們的缺點。」Orthogon Therapeutics結構生物副總裁Stephen Weeks博士說,「這項成就足證我們的平台確實有能力,可靶向過去無法成藥的病毒蛋白。」 這筆資金的到來,適逢Orthogon著手建立一款開創性動物模型以研究BK多瘤病毒病理學之際。在過去,研究人員並不清楚BK多瘤病毒如何在體內發展。這款模型可讓我

Orthogon Therapeutics完成超额认购的520万美元融资以推进BK多瘤病毒的首款口服治疗药物

[#item_full_content]马萨诸塞州坎顿–(BUSINESS WIRE)–(美国商业资讯)– 新型抗病毒药物开发商Orthogon Therapeutics今天宣布完成一轮超额认购,融资额超过500万美元的目标,使融资总额超过2500万美元。这笔资金将加速开发用于控制移植患者BK病毒再激活的先进治疗药物。 该公司已成功开发出直接针对多瘤病毒生命周期核心病毒蛋白的小分子药物。多瘤病毒缺乏传统的抗病毒蛋白靶点,几十年来一直未能开发出药物。凭借多元化的投资客户群和具有独特作用机制的药物管线, Orthogon正在解决这一尚未得到满足的迫切医疗需求。 Orthogon Therapeutics结构生物学副总裁Stephen Weeks博士表示,“我们的高亲和力小分子抗病毒药物可以与生物制剂相媲美,但却没有生物制剂的缺点。这项成果凸显了我们的平台能够靶向以前无法治疗的病毒蛋白。” 这一突破契合Orthogon建立研究BK多瘤病毒病理的开创性动物模型。 长期以来,研究人员缺乏对BK病毒疾病进展的体内研究。该模型加深了人们对疾病机制的理解,并为测试疗法提供了强大平台,巩固了Orthogon在解决多瘤病毒治疗障碍方面的领

CFPB announces rule limiting bank overdraft fees

[#item_full_content]The CFPB says the rule will save American consumers $5 billion annually.

Formic Announces Strategic Leadership Additions to Power Business Growth and Finance Infrastructure

[#item_full_content]CHICAGO–(BUSINESS WIRE)–Formic, a Robots-as-a-Service (RaaS) automation provider for U.S. manufacturers, officially announced the addition of Joel…

Orthogon Therapeutics fecha financiamento de US$ 5,2 milhões com excesso de inscrições para avançar a primeira terapia oral para poliomavírus BK

[#item_full_content]CANTON, Massachusetts–(BUSINESS WIRE)–A Orthogon Therapeutics, uma desenvolvedora de novos medicamentos antivirais, anunciou hoje o fechamento de…

Tenpoint Therapeutics Ltd. and Visus Therapeutics, Inc. Join Forces, Building the Next Era of Best- and First-in-Class Ophthalmic Medicines

[#item_full_content]LONDON & SEATTLE–(BUSINESS WIRE)–Tenpoint Therapeutics, Limited (“Tenpoint”) and Visus Therapeutics, Inc., (“Visus”) announce today the completion…

CFPB announces rule limiting bank overdraft fees

[#item_full_content]The CFPB says the rule will save American consumers $5 billion annually.

Here’s the inflation breakdown for November 2024 — in one chart

[#item_full_content]Increases in prices for groceries and gasoline outweighed disinflation in categories such as shelter, according to…

Here’s the inflation breakdown for November 2024 — in one chart

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China ramps up Wall Street meetings as Trump inauguration looms

[#item_full_content]Chinese Vice Premier He Lifeng has met with several U.S. finance executives as Beijing seeks to…

China ramps up Wall Street meetings as Trump inauguration looms

[#item_full_content]Chinese Vice Premier He Lifeng has met with several U.S. finance executives as Beijing seeks to…

China ramps up Wall Street meetings as Trump inauguration looms

[#item_full_content]Chinese Vice Premier He Lifeng has met with several U.S. finance executives as Beijing seeks to…

If Trump adds tariffs, ‘either way, there is a cost to consumers,’ economist says

[#item_full_content]President-elect Donald Trump’s tariff plan is expected to raise costs, especially for low and middle earners,…

If Trump adds tariffs, ‘either way, there is a cost to consumers,’ economist says

[#item_full_content]President-elect Donald Trump’s tariff plan is expected to raise costs, especially for low and middle earners,…

Orthogon Therapeutics Closes Oversubscribed $5.2M Financing to Advance First Oral Therapy for BK Polyomavirus

[#item_full_content]CANTON, Mass.–(BUSINESS WIRE)– #BKVAN–Orthogon Therapeutics, a developer of novel antiviral medicines, today announced the closing of…

FDA Grants Breakthrough Device Designation to MeMed Severity Test for Patients with Suspected Sepsis

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PricingDirect and Aumni Partner to Deliver Independent Valuations for Private Equity Securities

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Curql Fund II Makes History, Surpasses $200 Million in Investment Commitments—The Window to Join Is Still Open

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Amazon is bringing Intuit QuickBooks software to its millions of third-party sellers

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Amazon is bringing Intuit QuickBooks software to its millions of third-party sellers

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